ดร.จิรพัฒน์ คล้อยปาน

Chiraphat Kloypan

Department of Medical Technology
School of Allied Health Science
University of Phayao, Thailand
E-mail :


  • 2015-2019

Doctor of Medical Science (Dr. rer. medic)
Charité – Universitätsmedizin Berlin, Germany

  • 2012-2014

Master of Science (Medical Biochemistry)
Faculty of Medicine, Chulalongkorn University, Thailand

  • 2007-2011

Bachelor of Science (Medical Technology), Honour awarded
School of Allied Health Sciences, University of Phayao, Thailand

Research main interests

  • Fabrication and optimization of hemoglobin-based oxygen carriers.
  • Interaction of nanoparticles with blood and tumor cells.
  • Transportation and releasing of drug-loaded nanoparticles.
  • Hemocompatibility and biocompatibility of nano- and microparticles.

Published papers

  • Kloypan C, Suwannasom N, Chaiwaree S, Prapan A, Smuda K, Baisaeng N, Pruß A, Georgieva R, Bäumler H. In-vitro haemocompatibility of dextran-protein submicron particles. Artif Cells, Nanomedicine, Biotechnol. 2019;47(1):241–9.
  • Suwannasom N, Smuda K, Kloypan C, Kaewprayoon W, Baisaeng N, Prapan A, Chaiwaree S, Georgieva R, Bäumler H. Albumin Submicron Particles with Entrapped Riboflavin—Fabrication and Characterization. Nanomaterials. 2019;9(3):482.
  • Suwannasom N, Smuda K, Kloypan C, Kaewprayoon W, Baisaeng N, Boonla C, Georgieva R, Bäumler H. Detection of CD33 expression on monocyte surface is influenced by phagocytosis and temperature. Gen Physiol Biophys. 2019; 38: 369–78.
  • Prapan A, Suwannasom N, Kloypan C, Chaiwaree S, Steffen A, Xiong Y, Kao I, Pruß A, Georgieva R, Bäumler H. Surface Modification of Hemoglobin-Based Oxygen Carriers Reduces Recognition by Haptoglobin, Immunoglobulin, and Hemoglobin Antibodies. Coatings. 2019;9(7):454.
  • Kloypan C, Prapan A, Suwannasom N, Kaewprayoon W, Steffen A, Xiong Y, Baisaeng N, Georgieva R, Bäumler H. Improved Oxygen Storage Capacity of Haemoglobin Submicron Particles by One-Pot Formulation. Artif Cells, Blood Substitutes, Biotechnol.2018; DOI:10.1080/21691401.2018.1521819.
  • Bäumler H, Geogieva R, Kloypan C, Axel S, Xiong Y. One-pot formulation of biopolymer particles. European patent 23384-EP.
  • Chaikham S, Buatana J, Meethangdee M, Luang-apirom J, Sopin N, Jantabut K, Kloypan C, Nuttakorn B, Surapinit S. Alkaloids from Nauclea orientalis Inhibited in vitro ADP and Thrombin Induced Human Platelet Aggregation. Sci Technol Asia. 2017;22(2):61–7.
  • Kloypan C, Srisa-Art M, Mutirangura A, Boonla C. LINE-1 hypomethylation induced by reactive oxygen species is mediated via depletion of S-adenosylmethionine. Cell Biochem Funct. 2015;33(6):375–84.
  • Kloypan C, Jeenapongsa R, Sri-In P, Chanta S, Dokpuang D, Tip-Pyang S, Surapinit N. Stilbenoids from Gnetum macrostachyum attenuate human platelet aggregation and adhesion. Phyther Res. 2012;26(10):1564–8.